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The Intrinsically Disordered C-Terminal Domain Triggers Nucleolar Localization and Function Switch of PARN in Response to DNA Damage

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Poly(A)-specific ribonuclease (PARN). a multifunctional multi-domain deadenylase. is crucial to the regulation of mRNA turnover and the maturation of various non-coding RNAs. Despite extensive studies of the well-folding domains responsible for PARN catalysis. https://www.majesticmalinois.com/product-category/nipple-shield/
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