Background: Pediatric gastroenteropancreatic neuroendocrine tumors are exceedingly rare. resulting in most pediatric treatment recommendations being based on data derived from adults. Trametinib is a kinase inhibitor that targets MEK1/2 and has been employed in the treatment of cancers harboring mutations in the Ras pathway. Methods: We utilized an established human pediatric gastroen... https://www.cuttingedgecutleryco.shop/product-category/replacement-blade/
Preclinical evidence for employing MEK inhibition in NRAS mutated pediatric gastroenteropancreatic neuroendocrine-like tumors
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